Axin2 controls bone remodeling through the β-catenin–BMP signaling pathway in adult mice
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چکیده
منابع مشابه
Axin2 Controls Bone Remodeling through β-Catenin-BMP Signaling Pathway in Adult Mice
INTRODUCTION: Bone remodeling, a dynamic process involving bone resorption followed by bone formation, takes place throughout life to maintain bone homeostasis. Osteoporosis pseudoglioma (OPPG) syndrome and high bone mass (HBM) syndrome are both mapped to the locus of Lrp5, a receptor for Wnt ligands in activation of β-catenin signaling (1). OPPG patients harbor inactivating mutations in the Lr...
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ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 2009
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.051904